Premier League: Manchester United VS Tottenham Hotspur: prediction, possible lineups, head-to-head stats

Follow all of today's Football matches on our Live Match Centre

United's goalless stalemate against Newcastle at home last weekend increased the pressure on Erik ten Hag as he tries to lead his team to victory against Spurs.

United played to a scoreless tie against Newcastle United in their most recent match, while Antonio Conte's Chelsea team defeated Everton by a 2-0 margin.

Tottenham's performance against Everton was unremarkable at best, but Antonio Conte will not grumble about a third straight victory.

With a number of fine wins at Old Trafford under their belt in recent years, Spurs will want to dispel memories of last season’s collapse at the hands of a hat-trick from Cristiano Ronaldo.

Last season, Ronaldo turned back the clock with a hat trick to lead Man United to a 3-2 win in this fixture, which came a few months after the Red Devils triggered Nuno Espirito Santo's sacking with a 3-0 win in North London, and Conte is in danger of suffering a fourth consecutive defeat away to the Red Devils as a manager.

Meanwhile, Tottenham has recorded consecutive shutouts in the Premier League. And Conte will be hoping his top player, Harry Kane, can lead them to a historic triumph in Manchester thanks to his current wave of self-assurance.

Antonio Conte's team had to be patient to break down a stubborn Everton defence, but their persistence paid off as they are now tied for the third position with Manchester City on points after the champions' loss to Liverpool and ensured that their gap to leaders Arsenal would remain at four points.

Head-to-head, Manchester United has won 95 matches while Spurs clinched 53 of them. Whereas 49 games have been drawn.

Key stats:

• Man Utd have seen over 2.5 goals in their last five home matches against Tottenham
• Man Utd have scored at least three goals in their last three matches vs Tottenham
• Tottenham are undefeated in 15 of their last 16 PL matches
• Man Utd have won their last three matches against Tottenham in all competitions
• Man Utd are undefeated in 12 of their last 13 home PL matches
• The average number of goals in meetings between Manchester United and Tottenham is 4.2

Tottenham predicted lineup

There are new concerns for Tottenham ahead of Wednesday's encounter as Richarlison went down with a calf injury in the second half against Everton and was spotted exiting the stadium on crutches.

Conte has already ruled out the Brazilian for this match due to concerns that he may miss the World Cup, and Dejan Kulusevski is questionable after regressing in his recovery from a hamstring injury. And although Matt Doherty keeps on filling in as the starter, Emerson Royal will be sitting out the final game of his ban.

If Spurs' manager decides to go from his preferred 3-4-3 to a 3-5-2, Yves Bissouma is ready to make the transition back into midfield.

Probable lineup: Lloris; Romero, Dier, Davies; Doherty, Hojbjerg, Bissouma, Bentancur, Perisic; Son, Kane

Manchester United predicted lineup

Since Ten Hag will have to decide between dropping Cristiano Ronaldo and Jadon Sancho to make room for United's rising attacker Marcus Rashford, Rashford should be fit to start.

While Maguire and Martial are close to returning to action, they won't be a factor this week. On the other hand, Martin Dubravka and Scott McTominay, who were both ineligible or suspended last weekend, will be available again.

Probable lineup: De Gea; Dalot, Varane, Martinez, Malacia; Casemiro, McTominay; Antony, Fernandes, Sancho; Rashford

Tottenham Hotspur VS Manchester United predicted lineup

However, it is hard to pick Ten Hag's side to win against Conte's ever-improving squad, and at the moment, a low-scoring draw seems to be the most likely consequence of this Big Six fight.

Final prediction: United 2-2 Spurs